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Myxedema coma, management

Myxedema Coma: Diagnosis and Treatment - American Family

Patients with suspected myxedema coma should be admitted to an intensive care unit for vigorous pulmonary and cardiovascular support Myxedema coma or myxedema crisis is a life-threatening complication of hypothyroidism. Some symptoms of myxedema coma include fatigue, lethargy, depression, dry skin, and weight gain. Mild myxedema coma usually is treated by a general practitioner or internist while moderate to severe myxedema coma is treated and managed by an endocrinologist Patients with myxedema coma should be treated in an intensive care unit with continuous cardiac monitoring. Initial steps in therapy include airway management, thyroid hormone replacement,.. MANAGEMENT. Resuscitate. admit to ICU because if high mortality and multi-faceted therapy; may require intubation for various reasons (respiratory failure, airway obstruction from macroglossia, coma) ventilation may be required for several days -> weeks; IV fluid resuscitation and vasoactive agents until thyroid hormone action begin

Myxedema may be the first presentation of patients with undiagnosed hypothyroidism. Definitive management is with thyroid hormone but supportive measures, identification and treatment of precipitating factors in an appropriately safe environment are vital. There is no consensus about preferred thyro Description Myxedema coma is a life-threatening condition in which patients with underlying throid dysfunction exhibit exaggerated manifestations of hypothyroidism. Precipitating factors may include (but are limited to) infection, trauma, surgery, heart failure, stroke, or central nervous system depressants. Hypothyroidism depresses metabolic rate, thus seriously affecting all body system. Download Citation | Management of Myxedema Coma | Myxedema coma is the most severe manifestation of hypothyroidism. In spite of ready availability of sensitive thyrotropin assays, the recognition. {{configCtrl2.info.metaDescription}

Myxedema Coma Symptoms, Treatment, Causes & Hypothyroidis

  1. Myxedema coma is severe hypothyroidism leading to decreased mental status and slowed metabolism of multiple organs. It is a medical emergency with a high mortality rate. Airway management is complicated by myxedema airway swelling, so be prepared for a difficult airway. Bradycardia and hypotension: both are directly related to low cardiac.
  2. The therapeutic endpoints of levothyroxine therapy in patients with myxedema coma should be improved mental status, improved cardiac function, and improved pulmonary function. Thyroid hormones may be measured every 1 to 2 days. It is unclear what the optimal levels for serum TSH and thyroid hormones should be in this population
  3. Myxedema Coma is a misleading term: i) Most patients aren't truly comatose (but they are generally delirious). ii) Most patients don't have myxedema. The construct of myxedema coma sets clinicians up for diagnostic failure. Decompensated hypothyroidism may be conceptualized as hypothyroidism causing organ failure
  4. Myxoedema coma usually affects the mental state: patients may present with apathy, low mood, cognitive decline, confusion and even coma. The changes can be subtle and may be misdiagnosed as dementia or depression. Patients with myxoedema coma are commonly hypothermic with core temperatures less than 35.5°
  5. Myxedema coma, the extreme manifestation of hypothyroidism, is an uncommon but potentially lethal condition. Patients with hypothyroidism may exhibit a number of physiologic alterations to compensate for the lack of thyroid hormone. If these homeostatic mechanisms are overwhelmed by factors such as
  6. Management of Myxedema Coma. March 2020. Aydin Uzun Pinar; Myxedema coma is the most severe manifestation of hypothyroidism. In spite of ready availability of sensitive thyrotropin assays, the.
  7. Myxedema coma 1. By- Dr. D.kushbu 2. Myxedema coma is a state of decompensated hypothyroidism. A person may have lab values identical to a normal hypothyroid state, but a stressful event precipitates the myxedema coma state. 3. Primary symptoms of myxedema coma are altered mental status low body temperature. Low blood sugar, low.

Management. Primary treatment is prompted by the administration of adequate doses of either the thyroid hormone L-thyroxine given intravenously or by giving liothyronine via a nasogastric tube. It is essential to identify and treat the condition precipitating the coma. Myxedema coma is rare but often fatal MYXEDEMA COMA - MANAGEMENT. Myxedema coma is a medical emergency and must be treated rapidly. Levothyroxine sodium 400 µg is given intravenously as a loading dose followed by 100 µg intravenously daily. Other supplementary measures includ Suzanne Myers Adler, Kenneth D. Burman, in Clinical Management of Thyroid Disease, 2009. Myxedema Coma. Myxedema coma is an endocrinologic emergency and is the most clinically severe form of hypothyroidism. 64-66 Although it is rarely seen today, myxedema coma still carries a high risk of death unless treated promptly. Signs and symptoms include hypothermia, bradycardia, altered mental status. Myxedema coma is a rare but severe complication of myxedema. It is a life-threatening complication with a mortality rate of 25-60 percent and tends to affect older adults Myxedema coma can be prevented with early treatment of hypothyroidism, taking thyroid medication regularly, and recognition of the warning symptoms of myxedema coma. Outloo

Myxedema Coma or Crisis: Practice Essentials

Dr. Carlo Oller, emergency physician, talks about severe hypothyroidism, or myxedema coma Myxedema coma is the most severe manifestation of hypothyroidism. In spite of ready availability of sensitive thyrotropin assays, the recognition and treatment of myxedema coma remains a clinical challenge. It is typically caused by a precipitating event in an untreated or partially treated patient patient's management should in¬ clude determination of arterial blood gases and measures to pre¬ serve or restore normal alveolar ventilation. Complicationsof MyxedemaComa Dr. Birge: Hyponatremia and theinappropriatesecretionofADH oftencomplicatethe course of pa¬ tientswithmyxedemaandcoma. It maybeimportanttostress of theand the to (ADH) In.

Myxoedema Coma • LITFL • CCC Endocrin

Myxedema coma, the most severe form of hypothyroidism, is rare. It may be caused by an infection, illness, exposure to cold, or certain medications in people with untreated hypothyroidism. Symptoms and signs of myxedema coma include: Below normal temperature; Decreased breathing; Low blood pressure; Low blood sugar; Unresponsiveness; Primary Nursing Diagnosi Although the literature on emergent perioperative management of myxedema coma is scant, I advocate initially giving 10 micro g of IV T 3, or 5 micro g of IV T 3 in the elderly or in patients with coronary artery disease, followed by an IV T 4 bolus of 200-400 micro g (200 micro g/m 2), along with stress steroid coverage Myxedema coma, first reported in 1880 but not with frequency until 1953, remains poorly understood today. Progression from hypothyroidism to myxedema and finally to coma, while generally insidious, may be hastened by complicating illness or clouded by overlying myxedema psychosis. When coma occurs..

Myxedema Coma - PubMe

From a critical care point, pancytopenia should be managed as a part of a multisystemic complication of myxedema coma, knowledge of which can help guide management for critical care providers. Additional Points. Hypothyroidism is common and should be considered as part of the differential diagnosis in patients with abnormal hematologic parameters 2. Myxedema coma is a state of decompensated hypothyroidism. A person may have lab values identical to a normal hypothyroid state, but a stressful event precipitates the myxedema coma state. 3. Primary symptoms of myxedema coma are altered mental status low body temperature. Low blood sugar, low blooodpressure, hyponatremia ,. myxedema has a reversible behavior with the specific treatment [11]. The management of these manifestations focuses on hormonal supplementation, in some cases requiring inotropic and aminergic support. E. Gastrointestinal alterations There is a decrease in peristalsis; constipation is ver

Myxedema Coma Treatment. Treatment of myxedema coma usually involves emergency measures to reverse the condition and prevent death. Myxedema coma is highly fatal and patients usually die from cardiac and respiratory arrest. Patients are often placed in the intensive care unit for continuous monitoring and treatment Myxedema coma was described during the nineteenth century, but, despite the availability of specific hormonal therapy, the mortality rate remains high. This article discusses the causes, pathophysiology, and clinical presentation of myxedema coma. The differentiation of myxedema coma from the euthyroid sick syndromes is examined Myxedema coma is an extreme complication of hypothyroidism in which patients exhibit multiple organ abnormalities and progressive mental deterioration. the term myxedema is often used. Myxedema coma, occasionally called myxedema crisis, is a rare, life threatening clinical condition that represents severe hypothyroidism with physiologic decompensation

Introduction. Myxedema coma is a very rare endocrine emergency as a result of a very low synthesis of thyroid hormone due to some precipitating factors such as infections, hypothermia, heart failure, stroke, trauma, digestive bleeding, poor compliance of prescribed thyroid medications and drugs like lithium, sedatives, anesthesia [1] Myxedema coma is the most severe manifestation of hypothyroidism. In spite of ready availability of sensitive thyrotropin assays, the recognition and treatment of myxedema coma remains a clinical.. Hypothyroidism is a frequently diagnosed and simply treated disease. If not recognised, however, in time it may develop into the most severe manifestation of hypothyroidism known as myxedema coma. The term myxedema coma is generally seen as misleading since most patients do not initially present in a coma. The typical progression is lethargy evolving into stupor and, eventually, into coma with respiratory failure and hypothermia

Myxedema coma Nursing Management - RNpedi

Myxedema coma is one of the most severe potential consequences of profound, long‐standing hypothyroidism. Alternatively, myxedema coma may be triggered by an acute event such as infection (including sepsis), heart attack, stroke, injury, cold exposure, or the administration of drugs 5 Author: Tyler Hartman, M.D.Mayo Clinic Emergency Medicine Residency Progra

Unusual Clinical Scenarios to Consider in Patient Management. Myxedema coma is a life-threating illness that requires the expertise of an endocrinologist in terms of replacing thyroid hormone. Replacement of the hormone must be in very small doses, as standard doses may provoke life-threatening cardiac arrhythmias or myocardial infarction Management of AECOPD; Antibiotic therapy in AECOPD; Diabetes and related disorders. Diabetes mellitus type 1; Diabetes mellitus type 2; Diabetic ketoacidosis; Gestational diabetes mellitus; Hyperosmolar hyperglycemic state; Hypoglycemia; Epilepsy and Seizures. Epilepsy (seizure disorder) Absence seizures; Alcohol withdrawal syndrome. Key management points. Myxedema coma is a medical emergency and should be treated in an intensive care unit. The mainstays of therapy are 1) supportive care with ventilatory and hemodynamic. Myxedema coma occurs most often in the elderly and during the winter months; in one series, 9 of 11 cases of myxedema coma were admitted in late fall or winter. Myxedema coma is usually caused by a precipitating event in the untreated, or partially treated, hypothyroid patient

Myxedema Definition

Myxedema Coma and Thyroid Storm: Diagnosis and Management. Internal Medicine 14.Part 2 (2011): 1. Chu, Michael, and Terry F. Seltzer. Myxedema coma induced by ingestion of raw bok choy. New England Journal of Medicine 362.20 (2010): 1945-1946. Wall, Cristen Rhodes. Myxedema coma: diagnosis and treatment. American family physician 62.11. Myxedema crisis occurs when your body can no longer tolerate the changes caused by severe hypothyroidism, so it decompensates. This is a life-threatening state that requires immediate medical. A medical emergency, myxedema coma requires immediate attention. If the diagnosis is suspected, immediate management is necessary before confirming the diagnosis due to the high associated. Myxedema Coma :Findings Neck Thyroidectomy scar Goiter (uncommon) Dermatologic Dry, scaly, yellow skin Loss of lateral 3rd of eyebrows Non-pitting waxy edema of face / extremities 41. Myxedema Coma :Findings 42. Diagnosis• Diagnosis is clinical• Thyroid panel reflects chronic state 43 Myxedema coma: A rare and life-threatening complication of hypothyroidism (low levels of thyroid hormones in the bloodstream) characterized by loss of brain function (coma). Before a patient develops myxedema coma, features of hypothyroidism are usually present and may have gone unsuspected for a long period of time, including fatigue, lethargy, intolerance to cold, mental and mood changes.

1. Introduction. Myxedema coma is a severe and life-threatening form of decompensated hypothyroidism with an underlying precipitating factor. The mortality rates may be as high as 25-60% even with best possible treatment [1-5].The term myxedema coma is a misnomer, and myxedema crisis may be an apt term as quite a few patients are obtunded, rather than frankly comatose The diagnosis of myxedema coma is made when the three key diagnostic features of myxedema coma are present, which include altered mental status, hypothermia or absence of fever and a precipitating event such as cold exposure, infection, drugs. Diagnostic criteria Myxedema coma is a state of decompensated hypothyroidism.A person may have laboratory values identical to a normal hypothyroid state, but a stressful event (such as an infection, myocardial infarction, or stroke) precipitates the myxedema coma state, usually in the elderly.Primary symptoms of myxedema coma are altered mental status and low body temperature

Management of Myxedema Coma - researchgate

Management of myxedema coma: report on three successfully treated cases with nasogastric or intravenous administration of triiodothyronine. J Endocrinol Invest. J Endocrinol Invest. 1982 ;5: 331 - 334 Myxedema coma is a rare life-threatening endocrine emergency whose consequences include varying degrees of altered mental state, hypothermia, bradycardia, low cardiac output, hypoventilation, and pericardial effusion. The authors present the case of a man with a subdural hematoma triggering severe myxedema coma, resulting in a large pericardial effusion with subsequent cardiopulmonary arrest Myxedema coma is profound decompensated hypothyroidism usually precipitated by stressors, and its occurrence in association with total thyroidectomy or metabolic disorders, such as diabetic ketoacidosis, is unusual. A 43-year-old Asian man with history of total thyroidectomy who was scheduled for a second radioactive iodine therapy presented to our hospital with decreased mental status and. 1 Introduction. Myxedema coma (MC) is a rare but lethal clinical condition in patients with longstanding, severe, untreated hypothyroidism with an estimated incidence rate of 0.22 cases per million people per year. MC is a life-threatening emergency with mortality as high as 60%. MC in children is exceedingly rare with only few reported cases and limited therapeutic experience A. Immediate management. Once the diagnosis of myxedema coma is made, the patient should be transferred to an ICU (intensive care unit) setting. It is critical that thyroid replacement therapy begin immediately, but there are no large, prospective trials for myxedema coma, so dosing remains a question not answered by evidence-based medicine

of myxedema coma was 29.5% [ 10]. Past history of hypothyroidism can be a potential clue for the diagnosis of myxedema coma. However, a previous study had reported that 39% of patients with myxedema coma had Fig. 1 Chest X ray, computed tomography of the chest and abdomen, echocardiogram, and electrocardiogram Find all the evidence you need on Myxedema coma via the Trip Database. Helping you find trustworthy answers on Myxedema coma | Latest evidence made eas Myxedema is an ailment that is characterized by a thickened and enlarged skin. The condition is prompted by the reduced production of the thyroid hormone by the thyroid gland. Myxedema is merely brought about by hypothyroidism. Thyroid gland. Thyroid Gland Location n Structures. Cause

Hypothyroidism final

Find all the evidence you need on Myxedema Coma via the Trip Database. Helping you find trustworthy answers on Myxedema Coma | Latest evidence made eas Management of myxedema psychosis is similar to that of myxedema coma, with the ideal therapy remaining controversial, owing to the lack of clinical trials. Treatment in an ICU is recommended, with cardiac monitoring and monitoring for hyponatremia, hypoglycemia,.

The term myxedema coma is a misnomer, and myxedema crisis may be an apt term as quite a few patients are obtunded, rather than frankly comatose. As the disease is rare and unrecognized, we only have a few isolated case reports and case series, and there is a dearth of randomized controlled trials in the field of myx-edema crisis Myxedema Coma patients may appear fluid up with third spacing, but they are typically intravascularly dry. Consider monitoring with Inferior Vena Cava Ultrasound for Volume Status; Anticipate reflex vasodilation and Hypotension with rewarming; Rewarming. May treat Hypothermia with Passive Rewarmin

Myxedema Coma – Carlsibicky Internal Medicine APPE Blog

Myxedema Coma. Definition: life-threatening condition that occurs in patients with hypothyroidism due to severely low thyroid hormones (untreated or undiagnosed hypothyroidism).. Causes of Myxedema Coma. Occurs mainly in elderly women with hypothyroidism who have experienced: illness (respiratory or urinary infection Myxedema coma (MC) is a rare disorder characterized by severe hypothyroidism, presenting as altered mental status, hypothermia, and a decrease in the function of multiple organ systems. MC is a life-threatening condition with a high mortality rate; rapid recognition is critical to avoid end-organ damage

Thyrotoxicosis and myxedema-Anesthetic implications

Myxedema Coma 3,0,0,0 - UpToDat

Symptoms of myxedema coma should be monitored for efficacy of treatment. T4 and T3 levels should be monitored every 1-2 days to see if therapy is working. Once there is clinical improvement, oral therapy can be considered for the patient. Conclusion: Myxedema coma is a rare but severe form of hypothyroidism Myxedema coma is a loss of brain function as a result of severe, longstanding low level of thyroid hormone in the blood (hypothyroidism). Myxedema coma is considered a life-threatening complication of hypothyroidism and represents the far more serious side of the spectrum of thyroid disease

Endocrine emergencies overview

Myxedema coma is one of a long list of misnomer diagnoses in medicine; patients with the condition are rarely edematous or comatose. Dr. LoPresti prefers to use the term decompensated hypothyroidism. And it is decompensated hypothyroidism that we as ER Docs need to identify and treat in the emergency department Prevention of Myxedema Coma Because it is known how myxedema coma develops, it is obvious that there are ways to prevent its occurrence. The first thing and definitely the most important one is to have regular follow-up care and undergo regular blood testing in order to adapt hormone replacement therapy and make changes, if necessary

Home; Why eDucate? Patients. COVID-19. COVID-19 Disease. COVID-19 Disease (English) Protégez-vous contre COVID-1 Myxedema coma. This is the decompensated state of severe hypothyroidism in which the patient is hypothermic and unconscious. Medical Management. The primary objective in the management of hypothyroidism is to restore a normal metabolic state by replacing the missing hormone يتحدث هذا المقال عن تغيرات الجلد التي تحدث في حالة انخفاض هرمون الثايرويد (قصور الغدة الدرقية) , كلمة وذمة مخاطية كانت تستخدم على مرور التاريخ لتشير إلى قصور الغدة الدرقية بشكل عام.للحالات الطبية الطارئة ذات العلاقة. Liothyronine is indicated in adults and children for the treatment of coma of myxedema, the management of severe chronic thyroid... Type: Prescribing and Technical Information (Add filter

Don't get myxed up: Myxedema Coma and hypothyroidism

Myxedema coma, or severe hypothyroidism, is an emergent condition with a high mortality rate (30-60%). Our patients rely on us to catch it early and treat aggressively. About 90% of cases occur during the winter months, and it is rarely seen in patients younger than 60. Causes: Myxedema coma is usually precipitated by another condition Article Contents ::1 Myxedema coma 2 Myxedema coma Risk Factors3 Myxedema coma DIAGNOSIS —4 Myxedema coma Initial Lab Tests5 Myxedema coma Treatment Myxedema coma This is a state of hypothyroidism with altered con­sciousness or coma, sometimes seizures. There may be hypothermia. It is common in the elderly, and precipitated by seda-' tives, antidepressants, pneumonia, CHF, MI, [

American Thyroid Association Guideline: Treatment of

Myxedema coma typically presents as decreased mental status and hypothermia in a patient with either chronic, severe hypothyroidism or any form of hypothyroidism in the setting of a significant physiological stressor (infection, MI, sedative medications/opioids). Patients may also demonstrate hypotension, bradycardia, hypoventilation. Case report, diagnosis, emergency, myxedema coma, renal failure. Introduction Myxedema coma is typically a sequela of chronic severe thyroid hormone deficiency and is characterized by dete-rioration of mental status, hypothermia, hypotension, hyponatremia, and hypoventilation. It is one of the most urgent and lethal endocrine conditions. Criteria and scor-ing system for the diagnosis of myxedema coma, base patients; its use in patients with concomitant myxedema has not been studied [18, 19]. Patients who develop myxedema coma and subsequent cardiovascular collapse are rarely encountered in clinical practice. Myxedema carries a high mortality alone, and con-comitant coronary ischemia increases the complexity of the management for these patients

Decompensated Hypothyroidism (Myxedema Coma) - EMCrit

If myxedema coma is suspected, evaluation of thyroid stimulating hormone (TSH), free thyroxine (T4), and serum cortisol is warranted. T4 will be extremely low. TSH is variable depending on the etiology of hypothyroidism with a high TSH indicating primary hypothyroidism and a low or normal TSH indicating secondary etiologies Myxedema coma is a rare life-threatening complication of long-standing, neglected hypothyroidism. Till date only around 200 cases have been reported. We are reporting the case of an elderly lady with life-threatening myxedema coma and septicemic shock who was successfully treated with oral thyroxine

Myxoedema Coma. Information about Myxoedema Coma Patien

Myxedema coma is a severe form of hypothyroidism (low thyroid function). Myxedema coma occurs when thyroid hormone levels are not treated or controlled. Thyroid hormones help control body temperature, heart rate, growth, and weight. Myxedema coma can be triggered by not taking medicine to treat hypothyroidism Thyroid Storm and Myxedema Coma James Lantry III, John E. Arbo, and Geoffrey K. Lighthall BACKGROUND Thyrotoxicosis and myxedema coma are life-threatening syndromes representing the extremes of thyroid dysfunction. The rapid deterioration seen in these two conditions can result in significant morbidity and mortality if not promptly recognized.1 Delays in diagnosis and treatment are attributabl Myxedema Coma. Background. As the name implies, its main defining features include: myxedema (non-pitting edema) and coma (altered mental status). It is further described as a SEVERE, life-threatening state with decompensated low levels of thyroid hormone; Mortality can range from 25-60% despite treatmen Management. Patients with myxedema coma may present in extremis; implement initial resuscitative measures, including intravenous (IV) access, cardiac monitoring, and oxygen therapy, as indicated. Mechanical ventilation is indicated for patients with diminished respiratory drive or obtundation Myxedema coma, occasionally called myxedema crisis is a severe hypothyroidism condition. But, Dont worry Myxedema can be preventable and curable if we have a healthier life style and a proper hypothyroid medication intake. So, have a glance over Myxedema Symtoms, Causes & Treatment of Myxedema Coma

Myxedema coma: diagnosis and treatmen

There are no over-utilized or wasted diagnostic tests associated with the diagnosis of myxedema coma. III. Default Management. Until the TSH level is known and the diagnosis is made, default. A patient who was admitted with myxedema coma and diagnosed with hypothyroidism is improving and expected to be discharged in 2 days. Which teaching strategy will be best for the nurse to use? a. Provide written reminders of self-care information. b. Offer multiple options for management of therapies. c Myxedema coma is a rare and potentially fatal complication of hypothyroidism. While thyroid disorders — and hypothyroidism in particular — can lead to serious health issues, proper management and care can prevent risky health complications from occurring. One of those complications is myxedema coma

Management requires both medical and supportive treatment provided in the critical care setting. Myxedema Coma: Myxedema coma is a severe, life-threatening emergency that can occur in long-standing, untreated hypothyroidism. Diagnosis is based on laboratory results consistent with hypothyroidism and corresponding clinical manifestations Management of Myxedema coma ICU. admission is required for ventilatory support, continuous close monitoring of pulmonary and cardiac status IV medications General & supportive ABC 2. IV access-large bore 18 guage 3. Fluid replacement isotonic crystalloid solutions like NS/RL Avoid hypotonic solutions Avoid vasopressors-risk of dysrythmia 4 MYXEDEMA COMA - INTRODUCTION Myxedema coma is a life-threatening complication of hypothyroidism characterized by: altered consciousness slow breathing convulsions hypothermia (low body temperature) hyponatremia (low blood sodium level) and hypoglycemia (low blood glucose level) Myxedema coma can be triggered by exposure to cold, infection, trauma, drugs (such as sedatives and tranquilizers. Myxedema Coma Published by Jay Khadpe MD on February 5, 2015 February 5, 2015. Thanks to Dr. Lo Cascio for today's Morning Report! Case: 70 F BIBA with transcutaneous pacing pads on being paced at 80 bpm. Pt is unresponsive with SBP 170s. Pt is normothermic with FS 170. Pt has PMH of HTN, DM, ESRD (no missed dialysis)

Hypothyroidism Nursing Lecture NCLEX PathophysiologyThyroid Emergencies - Endocrine and Metabolic Emergencies

Myxedema, physiological reaction to lack of sufficient thyroid hormone (hypothyroidism) in the adult. It can be brought about by removal of the thyroid for any cause, by a cessation of function of the gland, or simply by glandular atrophy. The changes come on gradually: enlarged tongue; thickene Myxedema coma is a rare but severe complication of myxedema. It is a life-threatening complication with a mortality rate of 25-60 percent and tends to affect older adults. Symptoms of myxedema coma include a severe drop in body temperature, reduced breathing, and central nervous system failure, alongside other symptoms of hypothyroidism Myxedema coma occurs when thyroid hormone levels are not treated or controlled. Thyroid hormones help control body temperature, heart rate, growth, and weight. Myxedema coma can be triggered by not taking medicine to treat hypothyroidism. It may also be triggered by an infection, medicine, or a sudden stressful event, such as trauma or surgery.. Myxedema coma, occasionally called myxedema crisis, is a rare life-threatening clinical condition that represents severe hypothyroidism with physiological decompensation. The condition usually occurs in patients with long-standing, undiagnosed hypothyroidism and is usually precipitated by infection, cerebrovascular disease, heart failure.

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